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What types of drugs are EGFR inhibitors? Table 1. Current FDA-Approved EGFR Inhibitors Drug (Trade name) Class Target Cetuximab (Erbitux) ImClone, Bristol-Myers Squibb mAb EGFR Erlotinib (Tarceva) OSI Pharmaceuticals TKI EGFR Gefitinib (Iressa) AstraZeneca TKI EGFR Lapatinib (Tykerb) SmithKline Beecham TKI EGFR/HER2 1 more row
What is Iressa used to treat? IRESSA is a prescription medicine used to treat people with non-small cell lung cancer (NSCLC) that has spread to other parts of the body and: that have certain types of abnormal epidermal growth factor receptor (EGFR) genes, and.
What are the side effects of etoposide? Common side effects Increased risk of getting an infection. Breathlessness and looking pale. Bruising, bleeding gums or nosebleeds. Tiredness and weakness (fatigue) during and after treatment. Feeling or being sick. Hair loss. Loss of appetite. Constipation.
How is lung cancer formed? Lung cancer happens when cells in the lung change (mutate). They grow uncontrollably and cluster together to form a tumor. Lung cells most often change because they are exposed to dangerous chemicals that we breathe. Lung cancer symptoms usually do not appear until the cancer has spread to other parts of the body.
Does targeted therapy shrink tumors? Targeted cancer therapies block specific proteins or genes that help cancers grow and spread. For some types of cancer, they may work better than other treatments like chemotherapy. And targeted therapies can often stop working if the target changes or your cancer finds a way around the treatment.
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